The first Lion change you’ll notice is the login window. It’s different. But then once you get logged in and you start using Lion, you’ll notice that swiping around on a trackpad or mouse goes the wrong direction. No, your system isn’t broken, and no, don’t go filing any bugs with Apple. It’s supposed to be a more natural look and feel to moving around on screens. But I’m old and natural feels very unnatural (insert lewd joke here).
If you open System Preferences and click on trackpad (or mouse) then you’ll see all the gestures available to you. Click on the Scroll & Zoom tab and then uncheck the first box for Scroll direction: natural.
Ah… Much better… Having shown this, I would like to point out that I think this whole thing is the future, so you’re probably saving yourself a little grief if you get used to it now. But if you want to procrastinate a bit on this whole thing (like me), now you know how…